The Primary Structure of Epidermal Growth Factor
نویسندگان
چکیده
منابع مشابه
The primary structure of epidermal growth factor.
The complete amino acid sequence of epidermal growth factor (EGF) has been established through the use of automated Edman degradation and standard enzymatic and chemical techniques. The location of the half-cystinyl residues was facilitated by the use of the S-[14C]aminoethyl derivative of EGF. The sequence is: NH2-Asn-Ser-Tyr-ProGly5-Cys-Pro-Ser-Ser-Tyr1o-Asp-Gly-Tyr-Cys-Leu15-AsnGly-Gly-Val-C...
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The structure of mouse submaxillary gland epidermal growth factor (EGF) precursor has been deduced from complementary DNAs. The mRNA is approximately 4800 bases and predicts prepro EGF to be a protein of 1217 amino acid residues (133 X 10 Mr). EGF (53 amino acid residues) is flanked by polypeptides of 188 and 976 residues at its carboxy and amino termini, respectively. The amino terminus of the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1972
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)44569-9